My blue spruce which is over 30 foot tall and at least 15 feet wide is developing some dieout on branches starting from the inside. That is, branches are turning brown. This tree is almost 20 years old and has always been healthy and beautifully shaped. Should I spray with a fungicide?

Blue Spruce
It could be a number of issues. Spraying is not needed. List of problems.
-seasonal needle drop - see evergreen question. Natural.
-environmental stress, from uneven moisture.
If the tips of the branches are green don't worry. You might want to post a picture or bring a sample into your local Extension office.
Dennis - Johnson County Extension